Lamb: The Gospel according to Biff, Christ's Childhood Pal (2004) by Christopher Moore: This is a fictionalized account of Jesus' life from the point of view of his best friend. It's very silly, but it draws on topics of world religions, such as Judaism, Zen Buddhism, Taoism, and others, as it explores the beginnings of Christianity.
The Cutting Season (2012) by Attica Locke: This is a murder mystery, which also ties in an unsolved mystery of several generations ago. Both mysteries address the legacy of slavery, and how black people struggle to make sense of their past and heritage, especially in the context of white power structures.